GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs11148252 | 1 | rs11148252 | chr13:53009048 | CKAP2 | chr13:53029495-53050763:+ | -0.35 | -5.4 | 4.97E-7 | Lewy body disease |
| THYM | cis | rs2143950 | 1 | rs11156875 | chr14:35619816 | KIAA0391 | chr14:35591776-35786673:+ | 0.31 | 4.16 | 7.09E-5 | Atopic dermatitis |
| THYM | cis | rs2143950 | 1 | rs11156875 | chr14:35619816 | PPP2R3C | chr14:35554679-35591679:- | 0.25 | 4.71 | 8.36E-6 | Atopic dermatitis |
| THYM | cis | rs2985684 | 1 | rs11157696 | chr14:50105746 | RPL36AL | chr14:50085407-50087349:- | -0.26 | -4.26 | 4.89E-5 | Carotid intima media thickness |
| THYM | cis | rs2239557 | 1 | rs11159067 | chr14:74637444 | LIN52 | chr14:74551656-74667117:+ | 0.39 | 7.16 | 1.73E-10 | Common traits (Other) |
| THYM | cis | rs7552404 | 1 | rs11161511 | chr1:76210477 | ACADM | chr1:76190043-76229353:+ | -0.3 | -4.16 | 6.9E-5 | Blood metabolite levels;Acylcarnitine levels |
| THYM | cis | rs7969151 | 1 | rs11170680 | chr12:54161378 | COPZ1 | chr12:54718911-54745633:+ | -0.3 | -4.8 | 5.87E-6 | Tanning |
| THYM | cis | rs7969151 | 1 | rs11170681 | chr12:54165013 | COPZ1 | chr12:54718911-54745633:+ | -0.3 | -4.74 | 7.49E-6 | Tanning |
| THYM | cis | rs2066819 | 1 | rs11171803 | chr12:56718422 | RPS26 | chr12:56435686-56438005:+ | -0.83 | -4.32 | 3.91E-5 | Psoriasis vulgaris |
| THYM | cis | rs703842 | 1 | rs11172333 | chr12:58170335 | FAM119B | chr12:58166383-58176323:+ | 0.42 | 5.72 | 1.22E-7 | Multiple sclerosis |
| THYM | cis | rs703842 | 1 | rs11172333 | chr12:58170335 | TSFM | chr12:58176536-58191367:+ | -0.29 | -5.12 | 1.6E-6 | Multiple sclerosis |
| THYM | cis | rs703842 | 1 | rs11172335 | chr12:58175201 | FAM119B | chr12:58166383-58176323:+ | 0.42 | 5.72 | 1.22E-7 | Multiple sclerosis |
| THYM | cis | rs703842 | 1 | rs11172335 | chr12:58175201 | TSFM | chr12:58176536-58191367:+ | -0.29 | -5.12 | 1.6E-6 | Multiple sclerosis |
| THYM | cis | rs703842 | 1 | rs11172342 | chr12:58187758 | FAM119B | chr12:58166383-58176323:+ | 0.42 | 5.72 | 1.22E-7 | Multiple sclerosis |
| THYM | cis | rs703842 | 1 | rs11172342 | chr12:58187758 | TSFM | chr12:58176536-58191367:+ | -0.29 | -5.12 | 1.6E-6 | Multiple sclerosis |